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Definitions - About, Status, Availability; Conditions treated - Medicines replaced by or used in conjunction with, Alternatives, Substitutes; Treatments - Applications, Modalities, plus: How much? Dosage and Titration; Resources, Forums, News, sources. This page is an action item of MERCY. Learn more about MERCY.  

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Information on Canasol

Definition(s), About; What is it?

Canasol - Definition The Canasol Eyedrop | CANASOL was an ophthalmic drop solution prepared from cannabis sativa which contains 0.3% active solid. It was a Jamaican produced drug used for the treatment of the eye disease, glaucoma, was in high demand both on the local and international market. Canasol was developed through the hard work and scientific research of two notable Jamaicans: pharmacologist, Professor Manley West, and ophthalmologist, Dr Albert Lockhart. It was an important breakthrough drug as it was the first glaucoma eye medication in the Caribbean to be developed at UWI, Mona, and it did not induce the negative side effects that similar synthetic drugs were known for. * Read more History on Canasol

Status, Availability: Canasol was produced by Medi-Grace Pharmaceuticals. Medi-Grace Pharmaceuticals has been sold and does not produce Canasol anymore. Read more in the Resources section  

Conditions treated; How it works, Why?

Canasol - Definition Canasol was a cannabis-based medication for glaucoma that relieves intraocular pressure symptoms associated with late-stage glaucoma. Also, it did not induce the negative side effects that similar synthetic drugs are known for. Medicines replaced by or used in conjunction with Canasol; TBA ... Alternatives ... Substitutes

Canasol resource - Article; How Medical Cannabis Reduces Eye Pressure and Controls Eye Diseases How Medical Cannabis Reduces Eye Pressure and Controls Eye Diseases Cannabis has been proven time, and time again, to be a useful and effective anti-inflammatory for a range of different conditions. Many studies find that Cannabis reduces Glaucoma-related inflammation. "Canasol eyedrops, (a liquid Cannabis based formulation) has been demonstrated to be effective in lowering intraocular pressure, and has also been shown to potentiate the effectiveness of other widely-used glaucoma drugs such as Timolol." -- Dr. Manley West, Pharmacologist, University of the West Indies, Jamaica, Mon  Click >> HERE >> for more.


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Treating with Canasol; Applications, Modalities, plus: How much? Dosage and Titration

Canasol - Treatment Treatment with Canasol.   ... was 2-3 drops. * Read more History on Canasol ...

Canasol resource - Article; Information on Canasol and Medical cannabis (marijuana), in general Information on Canasol and Medical cannabis (marijuana), in general. | In 1964, Albert Lockhart and Manley West began studying the health effects of traditional cannabis use in Jamaican communities. They developed, and in 1987 gained permission to market, the pharmaceutical "Canasol", one of the first cannabis extracts.  Click >> HERE >> for more.

Canasol - Complications Complications of Canasol treatment.   TBA; there are no known complications due to Canasol to date.

Canasol resource - Toxicity; lethal dosage, contraindication with other medicines or side-effects Canasol (cannabis, "Marijuana") Toxicity ... Contraindications ... Side-effects ... TBA; there is no known lethal dose, contraindication with other medicines or side-effects to date.

Canasol resource - Article; CBD Oil For Glaucoma - Can It cure Glaucoma? CBD Oil For Glaucoma - Can It cure Glaucoma? | Cause Of Glaucoma: Glaucoma basically results from damage to the optic nerve. This is contributed majorly by the elevated pressure in the eye or the intraocular pressure. This in turn might be due to any blockage in the draining eye ducts, narrowing of the angle between the iris and the cornea, or due to degenerative changes. So anything that increases the intraocular pressure leads to glaucoma.

Cannabinoids And Glaucoma | With their increasing use in a variety of medical diseases, cannabis has also shown marked benefit in the treatment of glaucoma. According to studies, our eye has CB1 receptors that relate to the body's Endocannabinoidal system. This system is responsible for the body's homeostasis. Cannabis acts on our body by binding to these receptors. Their abundance in the eye makes feasible grounds for CBD to treat glaucoma. The mechanism of actions with which CBD treats glaucoma are as follows:

Reduces Intraocular Pressure: The presence of CB1 receptors in the ocular tissues help to regulate the production and outflow of the aqueous humor. This thus regulates the intraocular pressure.

Neuroprotective Action: Among the final stages of glaucoma, is also present the process of apoptosis, which leads to the death of the retinal ganglion cells. This ultimately causes blindness. Since CBD has neuro-protective effects, it prevents this process, and hence, decreases the chance of death of the retinal ganglion cells.

Miotic: Patients suffering from glaucoma also face a condition called Mydriasis, which means dilatation of the eye pupil. Increased dilatation may lead to further blockage of the ducts. Thus, CBD is used as a Miotic, which constricts the pupil and allows fluid adequate drainage.

Analgesic: Although glaucoma is usually painless, but in closed angle glaucoma, patients suffer from a stabbing pain in the eye ball. This may also be treated with the consumption of CBD as it makes a great analgesic.

Anti-Inflammatory: Since chronic cases of glaucoma are characterized by continuous minimal inflammation of the trabecular meshwork, the disease may get treated by CBD due to its promising role as an anti-Inflammatory.

Canasol - CBD Eye Drops For Glaucoma:: Canasol is the product name of Ganja-derived CBD eye drops for glaucoma, that are commercially available. Doctors say that the medication is non-psychoactive, and also highly effective in curing glaucoma. The product is present in Jamaica at the present, but is in high demand owing to its benefits.  Click >> HERE >> for more.

Canasol resource - Article; Pharmacologic THC and THC derivatives Pharmacologic THC and THC derivatives | In the USA, the FDA has approved several cannabinoids for use as medical therapies: dronabinol (Marinol) and nabilone. These medicines are taken orally. These medications are usually used when first line treatments for nausea and vomiting associated with cancer chemotherapy fail to work. In extremely high doses and in rare cases "psychotomimetic" side effects are possible. The other commonly used antiemetic drugs are not associated with these side effects. Canasol is a cannabis-based medication for glaucoma that relieves intraocular pressure symptoms associated with late-stage glaucoma.

It was created by an ophthalmologist, Dr. Albert Lockhart and Dr. Manley E. West, and began distribution in 1987.[97][98] As of 2003, it was still being distributed in the United Kingdom, several US states, and several Caribbean nations.[99] It is notable for being one of the first cannabis-containing pharmaceuticals to be developed for the modern pharmaceutical market and being one of the few such pharmaceuticals to have ever been legally marketed in the United States.[98][100]  Click >> HERE >> for more.

more on ... Pharmacologic THC and THC derivatives | and more on Medical cannabis ... refers to the parts of the herb cannabis used as a physician-recommended form of medicine or herbal therapy, or to synthetic forms of specific cannabinoids such as THC as a physician-recommended form of medicine.  Click >> HERE >> for more on this item.

Canasol resource - Class, Article; Dosage and administration guidelines for medical-grade marijuana Dosage and administration guidelines for medical-grade marijuana; inhalation, smoking, vaporization, oral ingestion, and sublingual delivery. | Dosage and Administration of Medical Cannabis: Cannabis has a remarkably wide margin of safety; thus, there is virtually no risk of death by overdose. Clinicians who have experience in the use of cannabis have found that the dosage will vary greatly among patients, even when treating the same condition. The basic principal for dosing is to start low and go slow. Prior to the marijuana prohibition, many of the pharmaceutical tinctures were highly concentrated, and the dosage was in "minums." The top of the container was a dropper to administer the medication. The label of an Ely Lily tincture of cannabis included dosage instructions that said: "DOSE 10–30 minums, increased till its effects are experienced."

In Jamaica, physicians have developed cannabis-based eye drops for glaucoma patients. Canasol and Canalol (cannabis and Timolol) are available by prescription in Jamaica (West, 1997). Drug Interactions | A drug interaction should always be considered when taking more than one medication. A problem with patients using cannabis is that they may not report their use of it to their healthcare provider because of its illegality, and this prevents the healthcare provider from monitoring for possible interactions. Cannabis and THC have been shown to alter the absorption and elimination of other drugs. Because of possible additive or synergistic action, cannabis should not be used in combination with alcohol, sedatives, or sleeping pills; increased sedation is one potential outcome. For patients using theophylline, cannabis will increase the metabolic processing of that drug. Because cannabis seems to work synergistically with opioids, patients may be able to decrease or cease their use of an opioid because they find they no longer need it.  Click >> HERE >> for more.

Glaucoma resource - Article; Glaucoma Treatment: Eye Drops and Other Medications Glaucoma Treatment: Eye Drops and Other Medications | Most treatments for glaucoma are designed to lower and/or control intraocular pressure (IOP), which can damage the optic nerve that transmits visual information to the brain. Glaucoma eye drops often are the first choice over glaucoma surgery and can be very effective at controlling IOP to prevent eye damage. If you are a good candidate for glaucoma eye drops, you may be prescribed more than one type to achieve the best IOP control. In fact, many types of these drops can enhance the effects of other types. Depending on your general health and other medical conditions, however, you may be a poor candidate for glaucoma eye drops. This is because medications placed in the eye are absorbed into the conjunctival blood vessels on the eye's surface. A certain percentage of the active ingredient of the medication, though small, will enter the bloodstream and may adversely affect functions such as heart rate and breathing.

Likewise, some types of eye drops may worsen certain existing medical conditions such as asthma. Some glaucoma drugs also can interact with other common medications such as digitalis, prescribed for heart conditions. So make sure you discuss these issues with both your family physician and your eye doctor. Types of Glaucoma Eye Drops | Glaucoma eye drops are classified by the active ingredient chemical that helps make the drug work. Also, many of the glaucoma eye drops listed here are available in generic forms at your pharmacy. Prostaglandins. Drugs known as prostaglandins used in eye drops often have the best user compliance because they are required only once daily. Prostaglandins generally work by relaxing muscles in the eye's interior structure to allow better outflow of fluids, thus reducing buildup of eye pressure.

These drugs have a few common side effects, including stinging and burning when put in the eye, eye color change (darkening of the eye) due to an increase of pigmentation in the iris, and lengthening and curling of the eyelashes. (In fact, the eyelash growth side effect eventually led to the development of an eyelash-lengthening drug called Latisse, which is available by prescription.) FDA-approved prostaglandins include Xalatan (Pfizer), Lumigan (Allergan), Travatan Z (Alcon) and Rescula (Novartis). Many glaucoma specialists now report that prostaglandins have taken the lead in recent years as a first-line therapy for glaucoma (EyeWorld, January 2007). Various glaucoma eye drops are classified by the active ingredient chemical that helps make the drug work. Beta-blockers. Used in a variety of glaucoma eye drops, beta-blockers were at one time the drugs of first choice in treating glaucoma. These drugs work by decreasing fluid (aqueous) production in the eye and now are often prescribed as an adjunct to or in combination with prostaglandins.

Alpha-adrenergic agonists. These drugs work by decreasing rate of aqueous humor production and can be used alone or in combination with other anti-glaucoma eye drops. Common side effects associated with this classification of eye drop include red or bloodshot eyes (ocular injection), upper lid elevation, an enlarged (dilated) pupil and itching. The FDA-approved drugs in this class include Iopidine (Alcon), Alphagan (Allergan). and Alphagan-P (Allergan). Carbonic anhydrase inhibitors. These drugs work by decreasing rate of aqueous humor production. They are usually used in combination with other anti-glaucoma eye drops and not alone. This classification of drug is also used in oral form (pills).

Common side effects experienced with this classification of eye drop include burning, a bitter taste, eyelid reactions and eye redness (ocular injection). The FDA-approved eye drops in this class include Trusopt (Merck) and Azopt (Alcon). The systemic (pill) form of carbonic anhydrase inhibitors (CAI) are Diamox (Sigma), Neptazane (Wyeth-Ayerst) and Daranide (Merck, Sharp, & Dohme). About half of patients cannot tolerate oral CAIs due to their systemic side effects, which include fatigue, depression, loss of appetite, weight loss, loss of libido, kidney stones, metallic taste and tingling in fingers and toes (peripheral neuropathies). *  SOURCE >> Click HERE >> *  Click >> - here - for more on medical cannabis and Glaucoma.


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Resources

Where to get, how to make: Medi-Grace Pharmaceuticals has been sold and does not produce Canasol anymore. We do not know of any other producer. Dr. West, RIP, has passed on - (Mar 17,1929 - Apr 24, 2012). MERCY does not have any Canasol nor do we know of a resource. There is a recipe for an eye-wash on our Bulletin Board.

CONTACTS

Canasol resource - Medi-Grace Pharmaceuticals Medi-Grace Pharmaceuticals | Medi-Grace Pharmaceuticals has been sold and does not produce Canasol anymore. Read more about the sale in the >> News section. We will post any information about any other Businesses in the >> Biz section of this page.

Canasol resource - Contact: Canasol and Asmasol Canasol and Asmasol | After ten years of continuous and diligent research, pharmacologist, Professor Manley West and ophthalmologist, Dr. Albert Lockhart developed an eye drop, Canasol, specifically to treat the eye disease, glaucoma. Glaucoma is estimated to affect 3% of the Jamaican population and causes pain, visual disturbances and even blindness.  Click >> - HERE >> for more and to make contact.

Canasol resource - Medi-Grace Pharmaceuticals Dr Albert Lockhart | Ophthalmologist, co-developer of Canasol * 7 Melmac Ave Kingston 5 Jamaica * 876-926-2750 -or- 876-926-8914  Click >> HERE >>

Canasol resource - Medi-Grace Pharmaceuticals Medicanja Limited | was established in December 2013 by Dr. Henry Lowe to chart the way forward in the development of a medical marijuana industry in Jamaica. Cannabis, known locally as ganja, has long been regarded as a plant with outstanding medicinal properties.  Learn more, click >> - HERE >>


Canasol - contacts; People, Organizations, Businesses and other resources. Got information?  Post it! People, Organizations, Businesses and other resources   will be listed here as we learn about them. Know of one? Post a Note, Send a Message, and Spread the Word!  

Forums

Canasol resource - Forums: My fiance started treatment for glaucoma 2 months ago. Forums > Medical Marijuana > Medical Marijuana Patients > Michigan Patients > Canasol is The Best Treatment for Glaucoma "The Eye Disease" | ( Jan 9, 2016 ) My fiance started treatment for glaucoma 2 months ago. She began using cannabis the day she was diagnosed. The best drug her doctor prescribed for her are just eye drops to reduce eye pressure. The combination of cannabis and the eye drops (she doesn't like the drops due to it making her eyes itchy) seem to be helping her very well. We are continuing to research for treatment. Original poster is not helping cannabis cause by trying to sell online with misinformation... Thank you for reply, do u know where can I buy the drops "canasol"? Coz my mum won't smoke...

fly down and buy it in jamaica, or find a jamaican (or other caribbean) friend. sorry, i have not been able to find any source for canasol anywhere. that gmail account above wanted $300 for a 5ml canasol bottle. hah!

you can fly round trip to jamaica for not much more than that. there might be a way to make your own cannabis oil for use as an eye drop, but i still do not have the recipe for creating your own eye drops.

I've known several Glaucoma patients who benefit from using cannabis, and they eat a small amount of an edible daily. One of them says that it's not enough to get her high, but her doctor tells her that it keeps her ocular pressure down. *  Click >> HERE >> for more and to contribute.

Canasol resource - Forums:  Canasol and ocular hypertension Canasol and ocular hypertension ( 02/25/2009 ) | hi to all!.. i'm new here.... i'm 28 years hold and my intraocular pression is 24... my oculist tell me to put drop of "timogel"... another one told me to put travatan.. 'cause timogel has too effects "unwanted"! i've read in internet that canasol reduce intraocular pressione.. anyone use it? does it really works? i'm in italy.. and here is illegal.. thanks in advance for your help... and sorry for my english! Login to read more... You must register because we have content that cannot be viewed unless you agree to our terms and conditions. *  Click >> HERE >> for more and to contribute.

Canasol resource - Forums: Medical Marijuana Doctors 420 Magazine > Forum > MEDICAL MARIJUANA >> Medical Marijuana Doctors | Canasol eye drops needed (04-24-2016) | I suffer from Glacouma .Can anyone tell me how purchase Canasol eye drops made from Cannabis it ?? Or a Doctor who will prescribe it ? Thank you , Moriah ...

FYI, I "HAD" glaucoma for about 20 years. Last June I started using cannabis for glaucoma and pain/inflammation. Last month when I had my eyes checked my pressures were lower than they have ever been and the doc said I could quit using them if I continued whatever I was doing. ... I have been using tinctures and eating cookies, along with smoking some now and then. Sorry I can't help with the drops ... *  Click >> HERE >> for more and to contribute.

Canasol resource - gouttes pour soigner un glaucome : le canasol - Phytotherapie gouttes pour soigner un glaucome : le canasol - Phytotherapie ... | bonjour je recherche une officine, un vendeur ou n'importe qui qui puisse me faire obtenir du canasol pour soigner efficacement mon glaucome ( dans les principes actifs du cannabis sativa il y a le thc et un autre principe c'est pas pour se droguer c'est pour se SOIGNER dans l'oeil il y aurait du mal , du reste ....!!!!!!!!!!!!!!!) ... je te propose un traitement organo a faire preparer en pharm. ( noter sur papier comme ci-dessous) corps ciliaire 15ch / corps ciliaire 18ch / aa qsp 125 ml corps ciliaire 30ch / foie 7ch / 40 gouttes au reveil et 15 mn avant le repas du soir + exercice occulaire et palming ...

Bonjour a tous, Je suis egalement a la recherche du canasol pour des raisons similaires a celles de General mais pour un stade de la maladie beaucoup plus avance...J'ai la quasi certitude de l'efficacite du produit et pourtant impossible de trouver un site de vente ou meme l'adresse d'une pharmacie a l'autre bout de la terre ... pourtant le temps presse. Donc si quelqu'un veut bien partager ses recherches avec les miennes, on arrivera peut etre a quelque chose. ...

Moi aussi je recherche ces gouttes "CANASOL", mais ou es t'il en vente ? Dans qu'elle pays ! Je serait prete a me deplacer ... C'est des gouttes a base de cannabis therapeutique ou des chercheur ont pris le principe actif du cannabis et qui ferait baisse la tension intraoculaire et qui n'a aucun effet indesirable ou secondaire ! Ces gouttes serait la solution pour les personnes atteinte de glaucome. Il ferait baisser la tension en quelques minutes. SVP si quelqu'un a des informations sur ce medicament, alors il faut absolument nous renseigner ! - Ou peut t'on nous le procure ? ... MERCI ! ...  Click >> HERE >> for more.


Canasol - Forums, Bulletin Boards, Chat rooms and other such online resources; 
	  Got information?  Post it! other Viable Forums, Bulletin Boards, Chat rooms and online resources   will be listed here as we learn about them. Know of one? Post a Note, Send a Message, and Spread the Word!  

News

Canasol resource - Article; How Medical Cannabis Reduces Eye Pressure and Controls Eye Diseases GraceKennedy Announces the Sale of MediGrace | GraceKennedy Limited announces the sale of Medi-Grace Limited to Smith Russell & Company Limited, a company which is engaged in the distribution of pharmaceutical and consumer products. It is expected that the sale will be completed by August 31, 2006. Medi-Grace Ltd. is involved in the distribution of pharmaceutical and consumer products, and represents such well known companies as Eli Lilly, Merck Sharp & Dohme, and Pfizer Consumer Health. It is expected that under the new ownership, Medi-Grace will continue to operate as an independent company focusing on the pharmaceutical industry. GraceKennedy Ltd. also operates a similar business which is involved in the distribution of consumer items called World Brands Ltd. Based on the terms of the agreement, certain consumer products with the brand names, Dial, Soft Sheen and Energizer now carried by Medi-Grace will be transferred to World Brands Ltd.  Click >> HERE >> for more.

Canasol resource - Article; Cannabis For Glaucoma Is The Real Deal; No Longer A Joke To Get A Medical Card, Marijuana Helps Glaucoma Cannabis For Glaucoma Is The Real Deal; No Longer A Joke To Get A Medical Card, Marijuana Helps Glaucoma | (Nov 10, 2016) Glaucoma patients are among the country's most prolific medical cannabis users. Cannabis has been shown to effectively reduce intra-ocular pressure (IOP) and in some cases can even halt the progression of glaucoma. Many studies since the 1970's have proven that cannabis is definitely effective in reducing IOP. One of the most recent studies conducted in 2014 shows that the cannabinoids in the plant are effective in reducing IOP in glaucoma patients. The study also found that cannabis possesses neuroprotective characteristics that can help patients prevent glaucoma. One of the most notable studies exploring cannabis for glaucoma dates back to the 60's. Professor Manley West, a pharmacologist, worked with ophthalmologist Dr. Albert Lockhart to research about the potential benefits of cannabis for the condition. They began to analyze cannabis use among Jamaican communities and even developed eye drops containing cannabis called Canasol, which was sold in Jamaica. Canasol was effective in reducing IOP, giving it as much potential as a treatment for glaucoma as conventional medications. Canasol is still used around the world and doesn't contain any of the psychoactive compounds of cannabis.  Click >> HERE >> for more.

Canasol resource - Article; Unravelling the Science behind Ganja Unravelling the Science behind Ganja | (June 6, 2016) The University of the West Indies has revived the ganja research programme it began in the 1970s as it prepares to launch Jamaica as a global "powerhouse" for cannabis research; as famous for its products and services as it already is for reggae and the good ‘ol sensi weed'. Aside from ongoing research into the properties and effects of Cannabis, the UWI was among the first in the world to successfully develop medicines from the plant. Its work, going back to 1972 when ophthalmologist Albert Lockhart and pharmacologist Dr. Manley West began investigating the anecdotes of fishermen who attributed their exceptional night-vision to their consumption of ‘ganja teas'.

From their research, the Department of Pharmacology in 1987 released the Canasol (TM), eye drops to treat glaucoma and followed that success in later years by a number of pioneering marijuana-derived pharmaceuticals: Asmasol for asthma; Cantivert also used to treat glaucoma; Canavert for motion sickness and Cansens for treating viral infections. "We are expecting that many products will be produced and have to be tested and quality checked for them to be marketed. We also expect the USDA will soon come up with regulations on cannabis-derived medicines and we are preparing to meet them," Lindsay said. Construction of the UWI Mona Cannabis Research Centre and supporting facilities to expand the institutions research capacity and house its partners is estimated to cost some US 4million dollars. McDonald is expecting that funding from partners will equip and build the facility as "their contribution to UWI's 40-year cannabis research legacy, accommodation and the prestige of brand-Jamaica".  Click >> HERE >> for more.

Canasol resource - News, Article; Jamaican ganja — the race against time; Three-day conference at UWI will tell law-makers opportunities slipping away Jamaican ganja — the race against time; Three-day conference at UWI will tell law-makers opportunities slipping away | (May 22, 2014) JAMAICA is already over 40 years behind in decriminalisation of ganja and a three-day conference which kicks off today at the University of the West Indies (UWI) will signal to legislators here that time is not on Jamaica's side. "We are 40 years late," said Dr Albert Lockhart, a leading opthalmologist who helped pioneer marijuana derived medicines such as Canasol for treating glaucoma, the eye disease and Asmasol for asthma sufferers.

Lockhart, and the late Dr Manley West of the UWI intensified medical research on ganja in 1972 after then Health Minister Dr Kenneth McNeill invited them to address parliamentarians on their work and gave them permission to collect, transport and do research on the weed within the bounds of Jamaica. He said Canasol changed the thinking of many persons about glaucoma when it hit the market. The drug gained favour with glaucoma sufferers because, unlike other drugs, it protected the optic nerve, while lowering eye pressure. "Our research found that when ganja was smoked it increased blood flow into the eye. That put us on to Canasol. We had to produce an eye drop because we don't promote smoking," Lockhart disclosed. "Anything smoked opens the smoker to cancer of the lips, throat and lungs," he noted. "Smoking of tobacco can cause heart problems."  Click >> HERE >> for more.

Canasol resource - Article; Latest developments in glaucoma therapy Latest developments in glaucoma therapy | (20/03/2014) Glaucoma has recently been reclassified as a "progressive optic neuropathy characterised by a specific pattern of optic nerve head and visual field damage." Now known to occur with or without elevated intraocular pressure, the updated definition of this group of irreversibly blinding disorders does not include the words intraocular pressure (IOP). Glaucomatous optic nerve damage should be seen as representing a final common pathway resulting from a number of diseases which affect the eye, similar to end-stage kidney or liver failure. Future additions to glaucoma therapy | Marijuana (cannabis): This definitely does lower intraocular pressure. CANASOL, an eye drop created from tetrahydrocannabinol (THC), the active ingredient in marijuana, is available in Jamaica. Unfortunately, although many other derivatives of marijuana have been tested in the US over the last 15 years, none has been deemed sufficiently effective and sufficiently free of side effects to bring to market there for glaucoma treatment.  Click >> HERE >> for more.

Canasol resource - Article; Give me credit for early work on Canasol Give me credit for early work on Canasol (September 11, 2013) | NOTE: Reference is made to Dr Albert Lockhart's letter to the editor titled 'Clarifying school of marijuana', which was published in The Gleaner on September 4, 2013. While I have no problem or issues with a gentleman like Dr Lockhart (who I have been associated with for decades) expressing his views, I was very surprised by his absolute negative statement: "I must point out that at no time was Dr Henry Lowe involved in the development of Canasol."

Factual history speaks for itself and, therefore, in my view, there is no need on my part for further dialogue on this subject beyond these points noted now or in the future: The work on Canasol can be said to have started in the science laboratories at CAST (now the University of Technology) soon after I returned from the University of Sydney School of Pharmacy in 1970, with an MSc in pharmaceutical/medicinal chemistry. The story of how the late Dr Manley West and I started this work is of great human interest and related to his observations on the Portland fishermen and how they could see the 'fish run' to get large catches after they smoke ganja.

The rest is history and the evidence exists to show that not only was I involved in the cannabis (ganja) research, but we authored at least one joint publication on this subject titled 'The Potential Use of Cannabis Sativa in Ophthalmology', West Indian Med Journal 1977 Jun;26(2):66-70. This article directly relates to the Canasol research and was subsequently quoted in several scientific publications. I go on further to say that when the Cannabis Research Institute was formed, with me being the first chairman in 2002, Dr West was invited to serve as a member of the board of directors. Dr West gave his full support to the venture and he told me, "It was a pity that I was never publicly referenced in any of the early recognition on glaucoma work on cannabis, particularly on the aspects of medicinal chemistry."

It was only since then that I started making reference to my involvement with the Canasol work, which few persons know about. I trust this will clear the air and we can move on with our scientific research and development to serve the world at large, but, more specifically, the people of Jamaica.  Click >> HERE >> for more.

Canasol resource - News, Article; Canasol and Cantimol, that effectively treat glaucoma Hemp Info > Hemp and Medicine > File Glaucoma >> Canasol and Cantimol, that effectively treat glaucoma. | (May 11, 2005) CONTROVERSY OR not, local scientists, Dr. Henry Lowe and Professor Errol Morrison note in their book the History of the use of Marijuana that ganja is liberally used by the folk in soups, cakes and cookies. The leaves are brewed and the tea taken as tonic or crushed and applied as an ointment to cure various conditions. In common folk preparations, the green leaves or buds are soaked in white rum (sometimes tempered with fruit juice) and used for the relief of stomach ache, toothache and symptoms of asthma. GLAUCOMA | On the issue of eye disease, glaucoma, the IOM report states that "the potential harmful effects of chronic marijuana smoking outweigh its modest benefits in treating glaucoma" and that more research is required to isolate, its therapeutic effect against high intraocular pressure (IOP). Most Jamaicans would already be aware that two highly-acclaimed local scientists, Drs. Manley West and Albert Lockhart, have already isolated ganja's therapeutic compound and have developed two drugs, canasol and cantimol, that effectively treat glaucoma. Cantimol is a combination of canasol, an alpha agonist and timolol maleate, a beta blocker.  Click >> HERE >> for more.

Canasol resource - News, Article; Ganja medicine in Jamaica Ganja medicine in Jamaica | (January 16, 2000) GLAUCOMA PRESSURE: Your eyes are infused with a fluid called aqueous humor that keeps them round, nourished and juicy. The pressure inside your eyes is called intraocular pressure, and is partially the result of a balance between the production, inflow and outflow of aqueous humor. If this balance is upset and your intraocular pressure rises to abnormally high levels, you are a victim of glaucoma. West explained that he and Lockhart began studying cannabis-glaucoma pharmacology in the early 1970's. Scientists had long known that cannabis lowered intraocular pressure, but instead of utilizing whole smoked cannabis, American researchers spent millions of dollars on a poorly-designed topical THC eyedrop treatment that had caused eye irritation and failed to decrease intraocular pressure.

Although early research and cultural lore indicated promising medical uses for ganja, West and Lockhart found their development of cannabis therapeutics complicated by drug war politics, as well as the daunting realities of pharmaceutical research, development and approval processes. Neither West nor Lockhart would elaborate on the exact procedures used to transform the above-mentioned solution into a prescription medicine, although Lockhart did say that a stable "powder" had been made in sufficient quantity to supply the experimenters with all the "principle" they needed to conduct numerous experiments and to make stable pharmaceutical preparations. Lockhart and West reported that clinical trials and anecdotal information indicate that Canasol is safe and effective. Lockhart said that the only problems they'd encountered occurred when a few vials of Canasol produced mild, temporary eye discomfort. The problem was corrected by creating a different type of vial.  Click >> HERE >> for more.

Canasol resource - Cannabis therapeutique - Les echos du Chanvre Cannabis therapeutique - Les echos du Chanvre | Des chercheurs jamaicains ont mis au point un traitement legal a base de cannabis pour traiter le glaucome, l'asthme et d'autres maladies. Le glaucome Les yeux sont proteges par un liquide appele humeur aqueuse. La pression dans les yeux est appelee pression intraoculaire et elle est en partie le resultat d'un equilibre entre la production, le flux et le reflux de l'humeur aqueuse. Si cet equilibre est perturbe et que la pression intraoculaire augmente anormalement, c'est un glaucome. ... "La Jamaique a une culture traditionnelle de la ganja", declare Lockhart. "Cela nous a aide a obtenir l'autorisation debut 1972 pour des protocoles de recherche etroitement reglementes et la collection de cannabis dans un but medical. Nous avons aussi reçu une aide commerciale du gouvernement dans les annees 80, ce qui nous a permis de creer une societe pour la fabrication et le marketing." ... Canasol, un medicament a base de cannabis qui permet de reduire la pression ... velle certification officielle pour le Canasol en fevrier 1983. "J'etais depuis ...  Click >> HERE >> for more.

Canasol resource - Article; Did you know that it was a Jamaican who: Created Canasol, a ganja-based eyedrop for glaucoma treatment Did you know that it was a Jamaican who: Created Canasol, a ganja-based eye-drop for glaucoma treatment | (Feb., 2014) Canasol was developed through the hard work and scientific research of two notable Jamaicans: pharmacologist, Professor Manley West, and ophthalmologist, Dr Albert Lockhart. It was an important breakthrough drug as it was the first glaucoma eye medication in the Caribbean to be developed at UWI, Mona, and it does not induce the negative side effects that similar synthetic drugs are known for. Professor West remembers being told by country folk that washing their eyes in ganja water made them see better, and fishermen claimed that drinking ganja tea improved their vision, particularly at night. Meanwhile, Dr. Lockhart noted that his Rastafarian patients who used ganja, had few incidences of glaucoma. From these observations, the two men became interested in working with ganja in order to discover its potential medical benefits. Ten years later, Canasol was the result.  Click >> HERE >> for more.

Canasol resource - Article: Cannabis Unmasked; What It Is and Why It Does What It Does Cannabis Unmasked; What It Is and Why It Does What It Does | (June, 2010) The Cannabis sativa plant has had a long, colourful and often controversial association with mankind. Originally cultivated to make hemp, a soft and durable fibre that was used extensively in the pre-industrial era for the production of rope, textiles and paper, it is also one of the oldest herbal remedies known to man, with texts from ancient China and India detailing its use as a treatment for a variety of illnesses. Even Queen Victoria of Britain is reported to have used it as a preparation for the treatment of menstrual cramps. Despite this wide variety of uses and its extensive commercial production (up to today over 40,000 hectares of hemp are under cultivation worldwide) cannabis is best known for its psychoactive properties and its association with recreational drug use (marijuana). A new era of understanding began in 1964 when the primary active ingredient of cannabis, delta-9-tetrahydrocannabinol (THC) was identified. Advances in cannabinoid physiology proceeded slowly over the next two decades but of note during this period was the contribution made by two Caribbean scientists, Manley West and Albert Lockhart. Based at UWI's Mona Campus, West and Lockhart started their journey in cannabinoid research when they noted (i) a reduction in glaucoma among Rastafarians who traditionally used cannabis and (ii) persons from rural communities who used eyewash purportedly derived from cannabis claimed improved eyesight. This triggered ten years of pioneering research that culminated with the development and patent of a drug, Canasol, for the treatment for glaucoma. *  Click >> HERE >> - for more.


Canasol - News; Articles, Stories, Sources and other resources. Got information?  Post it! News; Articles, Stories, Sources and other resources   will be listed here as we learn about them. Know of one? Post a Note, Send a Message, and/or Spread the Word!  

History

Canasol resource - Information: CANASOL, an ophthalmic drop solution According to various websites: CANASOL an ophthalmic drop solution prepared from cannabis sativa which contains 0.3% active solid. Canasol's research has proven this product effective to reduce the adverse symptoms of glaucoma by reducing intraocular pressure and having no side effects. This product has been approved by the Ministry of Health of Jamaica. Small wonder then that most new modern-day Cannabis based pharmaceuticals are making their appearance OUTSIDE of the US, in places like Jamaica. *  Click >> HERE >> - for more.

Albert Lockhart and Manley West began studying in 1964 the health effects of traditional cannabis use in Jamaican communities. They developed, and in 1987 gained permission to market, the pharmaceutical "Canasol", and began distribution in 1987. As late as 2003, it was still being distributed in the United Kingdom, several US states, and several Caribbean nations. It was notable for being one of the first cannabis-containing pharmaceuticals to be developed for the modern pharmaceutical market and being one of the few such pharmaceuticals to have ever been legally marketed in the United States.

The product, a derivative from cannabis (ganja, "marijuana"), was at first received with much scepticism and doubt, but according to ophthalmologist Dr. Albert Lockhart, one of the developers of the product, patients from Florida, California, Pennsylvania, Washington D.C., New York and Massachusetts in the United States were using it. "We have to try to educate people and let them know that Canasol does not contain any psychoactive agents" from ganja, he said.

The product was distributed in Jamaica by Medi-Grace Limited and, according to Dr. Lockhart, they also exported to England, some Caribbean islands, and it was sold directly based on doctor's prescriptions from the United States. According to sources at Medi-Grace Limited, an average of 400 units were sold per month, and pharmacists across Jamaica agreed that "the product sells like hot bread." "There is a great demand for the product," Mrs. C. Law a pharmacist at Dolphin's Pharmacy in Kingston said, adding that persons even send from abroad to get it.  Click >> HERE >> for more.

Canasol resource - Information: JAMAICA, THE LAND OF GENTLE BREEZES AND MEDICAL CANNABIS JAMAICA, THE LAND OF GENTLE BREEZES AND MEDICAL CANNABIS: | When one thinks of Jamaica, one usually thinks of travel, tourism, and white sandy beaches. However, it is now also gaining more and more attention as the land where (while still illegal) Cannabis medicines are beginning to flourish. CANASOL an ophthalmic drop solution prepared from cannabis sativa which contains 0.3% active solid. Canasol's research has proven this product effective to reduce the adverse symptoms of glaucoma by reducing intraocular pressure and having no side effects. This product has been approved by the Ministry of Health of Jamaica.  Click >> HERE >> for more on this. *  Click >> here << for more on medical cannabis in Jamaica.

Canasol resource - Information: Renowned Jamaican scientist Dr. Manley West Renowned Jamaican scientist Dr. Manley West | Dr West was a scientist. He taught pharmaco-logy at the University of the West Indies, Mona. Significantly, with Dr Albert Lockhart, he developed Canasol, a drug for the treatment of the eye disease, glaucoma, from cannabis, or ganja. Born in Portland, West attended the Titchfield High School. He graduated from the University of London, England, in 1967 with a Doctor of Philosophy in pharmacology. His career at the UWI began as assistant lecturer in pharmacology in 1964, from which position he was promoted to lecturer and internal examiner in pharmacology in 1968. Thereafter, in 1975, West served as acting head of the Department of Pharmacology and in that same year was appointed head of the Department of Pharmacology and chief internal examiner. He was appointed professor of pharmacology in 1981. *  Click >> HERE >> - for more.

Canasol resource - Medi-Grace Pharmaceuticals Professor the Hon. Manley West, OM | (Mar 17,1929 - Apr 24, 2012) Pharmacologist who conducted pioneering research of the marijuana plant, leading to the development of specialty medicines for glaucoma and other disorders. Glaucoma is a leading cause of preventable blindness and is estimated to affect three per cent of the Jamaican population. Today, many persons worldwide affected by disease are receiving relief through the use of the drugs developed from this research done at the Mona Campus.  SOURCE >> - HERE >>


Canasol - History; about Canasol and related. Got information?  Post it! more History about Canasol and related;   will be listed here as we learn about it. Got info? Post a Note, Send a Message, and/or Spread the Word!  

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Enter questions, comments and link info in the NotePad. If you leave info about an Archived item, it will be updated as soon as we can (and following approval). To request further maintenance, use the Feedback form.

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Thursday, September 14, 2017 at 03:25 AM:
Morgane from France wrote:
" je cherche un remede pour ralentir mon glaucome. Cordialement "

On 5/25/2017 3:25 AM, Velcro wrote:
" Years ago, I started using Herbal Eyebright. It really helped my eyes. My husband's eye specalist said he might be getting Glaucoma and prescribed this expensive eyedrops.

I got my MMJ card renewed and bought some bud with high CBD. Decided to try making an eyewash with it. Took 1 C boiling distilled H2O, added a small amt of AC/DC into it, let it steep for about 15 min and strained it. Hubby has been using it for several days, says he can see better. He had cataracts surgery several years ago and they have come back. He's hoping the eyewash will cure his glaucoma and remove the cataracts.

The people of Jamaica are ahead of us. Will be curious to see if anyone else has used MMJ as an eyewash. "

Monday, October 24, 2016 at 05:28 AM:
Leona Hardin from Plateau, OK wrote:
" now been I Lancaster, PA for 3 year ... where is how do u sign up for it medical marijuana card? "

Wednesday, January 20, 2016 at 07:21 AM:
John Wright from Kingston, Jamaica, but currently ljives in New Jersey wrote:
"I have been diagnose with high eye pressure and my doctor is reccommending laser surgery. Do you know where i can get Canasol to buy to treat my eyes. My email address is >> jwright132@yahoo.com "

Tuesday, July 15, 2014 at 03:09 AM:
Helder Nunes (Naturopatic Doctor) from Portugal wrote:
"I need to treat my mother´s glaucoma with Canasol and I just don´t know how I can buy it. Can somebody help me? Thanks "

Monday, November 4, 2013 at 11:14 AM:
Nobody Special from Here wrote:
" I ask you where to find info and do research about the various chemical components of cannabis. I have glaucoma and can't get Canasol so am wanting to experiment to see if I can make an eye drop that is also effective to lower eye pressures- or to connect with a person who is already doing this. I think I heard that the CBDs are best in a 4-1 ratio with THC for the best lowering of IOPs but I want to have more specifics if I can find them! It seems as though a water- based solution is the one best for the eye drop and also most effective for lowering the IOPs...so do you know if CBDs are water-soluble? and what is their source?- which part of the plant- ie leaves rather than bud? or a particular strain of cannabis best for CBDs? "


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About this page | Info, Orgs, Links and other Resources for Canasol, a cannabis-based treatment. You are visitor # 64!  (since m/d/20y)  Thanx for stopping by. Tell your friends. Tell your enemies!   This page ( /libry/i_CanasolY.html ) was last modified on:  Tuesday, 26-Dec-2017 06:18:26 PST